The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed because of a cast error
Error code: DatasetGenerationCastError
Exception: DatasetGenerationCastError
Message: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 3 new columns ({'SMILES', 'IDType', 'ID'}) and 7 missing columns ({'NumActiveCompounds', 'Description', 'URL', 'Reference', 'Paper Title', 'Assay Name', 'AID_confirmatory'}).
This happened while the csv dataset builder was generating data using
hf://datasets/maomlab/ChAFF/data/Absorbance.csv (at revision da0d7cd86fa09912e506f0889c911408061b0697)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback: Traceback (most recent call last):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
writer.write_table(table)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/arrow_writer.py", line 644, in write_table
pa_table = table_cast(pa_table, self._schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2272, in table_cast
return cast_table_to_schema(table, schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
raise CastError(
datasets.table.CastError: Couldn't cast
Type: string
DatasetName: double
AID: int64
ID: int64
IDType: string
SMILES: string
-- schema metadata --
pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 921
to
{'Type': Value('string'), 'DatasetName': Value('string'), 'AID': Value('float64'), 'AID_confirmatory': Value('float64'), 'NumActiveCompounds': Value('int64'), 'Paper Title': Value('string'), 'Reference': Value('string'), 'URL': Value('string'), 'Assay Name': Value('string'), 'Description': Value('string')}
because column names don't match
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1456, in compute_config_parquet_and_info_response
parquet_operations = convert_to_parquet(builder)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1055, in convert_to_parquet
builder.download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 894, in download_and_prepare
self._download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 970, in _download_and_prepare
self._prepare_split(split_generator, **prepare_split_kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1702, in _prepare_split
for job_id, done, content in self._prepare_split_single(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
raise DatasetGenerationCastError.from_cast_error(
datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 3 new columns ({'SMILES', 'IDType', 'ID'}) and 7 missing columns ({'NumActiveCompounds', 'Description', 'URL', 'Reference', 'Paper Title', 'Assay Name', 'AID_confirmatory'}).
This happened while the csv dataset builder was generating data using
hf://datasets/maomlab/ChAFF/data/Absorbance.csv (at revision da0d7cd86fa09912e506f0889c911408061b0697)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
Type
string | DatasetName
null | AID
float64 | AID_confirmatory
null | NumActiveCompounds
int64 | Paper Title
string | Reference
string | URL
null | Assay Name
string | Description
string |
|---|---|---|---|---|---|---|---|---|---|
Absorbance
| null | 632
| null | 43
|
A Novel Class of Small Molecule Inhibitors of Hsp90
|
(Yi, 2008, 10.1021/cb800162x)
| null |
Confirmation Concentration-Response Assay and Counterscreen for Disrupters of an Hsp90 Co-Chaperone Interaction
|
Interference compounds have a score of 10
|
Absorbance
| null | 1,641
| null | 92
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
TR-FRET counterscreen for FAK inhibitors: dose-response biochemical high throughput screening assay to identify inhibitors of Proline-rich tyrosine kinase 2 (Pyk2)
|
TR-FRET counterscreen for FAK inhibitors
|
Absorbance
| null | 1,730
| null | 10
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
Counterscreen Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay
|
Counterscreen Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay
|
Absorbance
| null | 1,857
| null | 290
| null | null | null |
FRET-based counterscreen assay for selective VIM-2 inhibitors: biochemical high throughput screening assay to identify epi-absorbance assay artifacts
|
FRET-based counterscreen assay to identify epi-absorbance assay artifacts
|
Absorbance
| null | 1,926
| null | 118
| null | null | null |
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
|
FRET-based counterscreen assay to identify epi-absorbance assay artifacts
|
Absorbance
| null | 435,026
| null | 507
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
Fluorescence Cell-Free Homogeneous Counterscreen to Identify Inhibitors of the RanGTP-Importin-beta complex
|
fluorescence resonance energy transfer (FRET)-based biochemical assay used as counterscreen
|
Absorbance
| null | 504,689
| null | 59
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
|
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
|
Absorbance
| null | 720,541
| null | 416
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
qHTS for Inhibitors of the Phosphatase Activity of Eya2: Carboxyl-terminal binding protein (CtBP) Counterscreen for Cherry-picked Compounds
|
Carboxyl-terminal binding protein (CtBP) Counterscreen for Cherry-picked Compounds
|
Absorbance
| null | 1,159,604
| null | 51
|
Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies
|
(David, 2019, 10.1002/cmdc.201900395)
| null |
Counterscreen for inhibitors of ASK1: AlphaScreen-based biochemical high throughput dose response assay to identify inhibitors that optically interfere with alphascreen assays using TruHits beads
|
Counterscreen for inhibitors of ASK1: AlphaScreen-based biochemical high throughput dose response assay to identify inhibitors that optically interfere with alphascreen assays using TruHits beads
|
Artifact
| null | 485,270
| null | 701
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 1,040
| null | 501
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 628
| null | 1,396
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 1,672
| null | 942
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 449,739
| null | 940
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 2,239
| null | 175
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 2,661
| null | 191
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 488,975
| null | 383
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 504,558
| null | 48
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 2,098
| null | 923
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 624,304
| null | 1,150
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 485,273
| null | 1,119
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 873
| null | 853
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 2,221
| null | 243
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 720,511
| null | 548
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 686,996
| null | 393
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Artifact
| null | 1,832
| null | 446
|
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery
|
(Boldini, 2024, 10.1021/acscentsci.3c01517)
| null | null |
One of Boldini2024 dataset which contains 13 different subdatasets.
|
Autofluoresence
| null | 587
| null | 34
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in Texas Red Spectral Region
| null |
Autofluoresence
| null | 588
| null | 25
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in Resorufin Spectral Region
| null |
Autofluoresence
| null | 589
| null | 6,214
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region
| null |
Autofluoresence
| null | 590
| null | 6,427
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region
| null |
Autofluoresence
| null | 591
| null | 59
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in A488 Spectral Region
|
A488 Spectral Region; 480 nm and 540 nm excitation and emission
|
Autofluoresence
| null | 592
| null | 0
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in A647 Spectral Region
| null |
Autofluoresence
| null | 593
| null | 532
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in Fluorescein Spectral Region
|
480 nm and 540 nm excitation and emission
|
Autofluoresence
| null | 594
| null | 32
|
Fluorescence spectroscopic profiling of compound libraries
|
(Simeonov, 2008, 10.1021/jm701301m)
| null |
qHTS Assay for Spectroscopic Profiling in Rhodamine Spectral Region
| null |
Autofluoresence
| null | 709
| null | 3,590
| null | null | null |
Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm
|
Autofluorescence at 339/460 nm; For fluorescent compounds, Dye equivalent concentration at given concentration > 10μm/ Fold Increase at 10μm; Blue non-fluorescent compounds need to be validated more than three times, while green non-fluorescent compounds should be validated more than five times.
|
Autofluoresence
| null | 923
| null | 779
|
A small molecule inhibitor of Caspase 1
|
(Boxer, 2010, https://www.ncbi.nlm.nih.gov/books/NBK56241/)
| null |
qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region
|
405 nm excitation/520 nm emission
|
Autofluoresence
| null | 1,480
| null | 89
|
Title: Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2
|
(Strouse, 2010, https://pubmed.ncbi.nlm.nih.gov/23658968/)
| null |
Profiling compound fluorescence in IgMXP3 at 488/530 nm; counter screen to single point confirmation of ABCG2 screen
|
in IgMXP3 cells (ABCG2) 488/530 nm
|
Autofluoresence
| null | 1,483
| null | 83
|
Title: Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2
|
(Strouse, 2010, https://pubmed.ncbi.nlm.nih.gov/23658968/)
| null |
Profiling compound fluorescence in CCRF-Adr at 488/530 nm; counter screen to single point confirmation of ABCB1 screen
|
in CCRF-Adr (ABCB1 expressing cells) at 488/530 nm
|
Autofluoresence
| null | 1,696
| null | 342
|
Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy- D-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)
|
(Sivendran, 2010, 10.1016/j.bmc.2009.11.033)
| null |
Rml C and D fluorescent artifact dose-response confirmation
|
340/460 nm
|
Autofluoresence
| null | 1,775
| null | 825
| null | null | null |
Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission
|
on Avidin Beads with 488 nm excitation and 530 nm emission
|
Autofluoresence
| null | 1,776
| null | 489
| null | null | null |
Profiling compound fluorescence on GSH Beads with 488 nm excitation and 530 nm emission
|
on GSH Beads with 488 nm excitation and 530 nm emission
|
Autofluoresence
| null | 2,124
| null | 198
| null | null | null |
Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caused By Cell-Permeable Autofluorescent Compounds
|
488nm excitation / 535 nm emission
|
Autofluoresence
| null | 2,757
| null | 9
| null | null | null |
Test compound autofluorescence in Saccharomyes cerevisiae specifically s288c
|
520 nm emission in Saccharomyes cerevisiae s288c
|
Autofluoresence
| null | 588,517
| null | 63
| null | null | null |
Compound fluorescence counter screen for HTS for inhibitors of efflux pump with Cherry Pick1 compound set
|
488 nm excitation
|
Autofluoresence
| null | 588,620
| null | 13
| null | null | null |
Dose response compound fluorescence counter screen for HTS for inhibitors of efflux pump with Hit compounds from Cherry Pick1
|
488 nm excitation
|
Autofluoresence
| null | 624,483
| null | 10,930
| null | null | null |
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease
|
Spherotech Blue Array Particle kit
|
Autofluoresence
| null | 720,675
| null | 21
| null | null | null |
qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells
|
535 nm (green) in HepG2 cells
|
Autofluoresence
| null | 720,678
| null | 35
| null | null | null |
qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells
|
460 nm (blue) in HEK293 cells
|
Autofluoresence
| null | 720,680
| null | 13
| null | null | null |
qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells
|
535 nm (green) in HEK293 cells
|
Autofluoresence
| null | 720,681
| null | 37
| null | null | null |
qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture
|
460 nm (blue) in HEK293 cell
|
Autofluoresence
| null | 720,682
| null | 13
| null | null | null |
qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture
|
535 nm (green) in HEK293 cell
|
Autofluoresence
| null | 720,686
| null | 20
| null | null | null |
qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture
|
535 nm (green) in HepG2 cell
|
Autofluoresence
| null | 720,687
| null | 32
| null | null | null |
qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells
|
460 nm (blue) in HepG2 cells
|
Autofluoresence
| null | null | null | 216
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 80
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 39
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 209
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 80
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 37
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 210
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 56
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 33
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 224
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 44
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
Autofluoresence
| null | null | null | 34
|
High-Throughput Screening to Predict Chemical-Assay Interference
|
(Borrel, 2020, 10.1038/s41598-020-60747-3)
| null | null |
One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets.
|
ColloidalAggregators
| null | 585
| null | 1,256
|
SCAM Detective: Accurate Predictor of Small, Colloidally Aggregating Molecules
|
(Alves, 2020, 10.1021/acs.jcim.0c00415)
| null |
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent)
| null |
ColloidalAggregators
| null | 1,476
| null | 4,500
|
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease
|
(Jadhav, 2010, 10.1021/jm901070c)
| null |
qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent)
|
Inhibitors of Cruzain (without detergent)
|
ColloidalAggregators
| null | 485,341
| null | 1,730
|
SCAM Detective: Accurate Predictor of Small, Colloidally Aggregating Molecules
|
(Alves, 2020, 10.1021/acs.jcim.0c00415)
| null |
qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent)
|
qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent)
|
ColloidalAggregators
| null | null | null | 12,644
|
An Aggregation Advisor for Ligand Discovery
|
(Irwin, 2015, 10.1021/acs.jmedchem.5b01105)
| null | null |
20 diverse sources
|
HeavyHitters
| null | null | null | 13,068
|
Modeling Small-Molecule Reactivity Identifies Promiscuous Bioactive Compounds
|
(Matlock, 2018, 10.1021/acs.jcim.8b00104)
| null | null |
PubChem2016, non-ChEMBL tested in at least 100 assays
|
HeavyHitters
| null | null | null | 1,000
|
Statistical models for identifying frequent hitters in high throughput screening
|
(Goodwin, 2020, 10.1038/s41598-020-74139-0)
| null | null | null |
HeavyHitters
| null | null | null | 16,820
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 8,441
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 12,092
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 4,871
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 6,056
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 8,089
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
HeavyHitters
| null | null | null | 1,544
| null |
(Shi, 2024, 10.1093/nar/gkae424)
| null | null |
One of Shi2024 dataset which contains seven different subdatasets.
|
LuciferaseInhibition
| null | 411
| null | 1,571
|
Characterization of chemical libraries for luciferase inhibitory activity
|
(Auld, 2008, 10.1021/jm701302v)
| null |
qHTS Assay for Inhibitors of Firefly Luciferase
|
ATP concentration in the assay (10 uM)
|
LuciferaseInhibition
| null | 1,006
| null | 2,976
|
Characterization of chemical libraries for luciferase inhibitory activity
|
(Auld, 2008, 10.1021/jm701302v)
| null |
Counter Screen for Luciferase-based Primary Inhibition Assays
|
with >50% inhibition at 10 uM concentration
|
LuciferaseInhibition
| null | 1,379
| null | 565
|
A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution
|
(Auld, 2009, 10.1021/jm8014525)
| null |
Counterscreen for Luciferase (Kinase-Glo TM) Inhibition
| null |
LuciferaseInhibition
| null | 1,891
| null | 446
| null | null | null |
Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase
|
EC50 <= 1 log over the highest tested concentration
|
LuciferaseInhibition
| null | 2,515
| null | 10
| null | null | null |
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Probe SAR
|
NIH Chemical Genomics Center (NCGC) Assay
|
LuciferaseInhibition
| null | 2,530
| null | 46
| null | null | null |
Secondary Assay for Luciferase (Kinase-Glo TM) Inhibition Counterscreen
| null |
LuciferaseInhibition
| null | 366,887
| null | 8
| null | null | null |
Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assay
|
activity <= 10uM
|
LuciferaseInhibition
| null | 366,889
| null | 1
| null | null | null |
Inhibition of Photinus pyralis luciferase assessed as maximum inhibitory potency by quantitative high throughput screening
|
activity <= 10uM
|
LuciferaseInhibition
| null | 366,891
| null | 19
| null | null | null |
Inhibition of luciferin binding site of Photinus pyralis luciferase by competitive inhibition assay
|
activity <= 10uM
|
LuciferaseInhibition
| null | 488,838
| null | 41
| null | null | null |
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR
| null |
LuciferaseInhibition
| null | 493,175
| null | 0
| null | null | null |
miR-21 counterscreen using purified firefly luciferase
| null |
LuciferaseInhibition
| null | 588,342
| null | 25,069
|
Firefly luciferase in chemical biology: a compendium ofinhibitors, mechanistic evaluation of chemotypes, and suggested use as areporter.
|
(Thorne, 2012, 10.1016/j.chembiol.2012.07.015)
| null |
qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project)
| null |
LuciferaseInhibition
| null | 588,498
| null | 18
| null | null | null |
qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for the Campaign to Identify EBNA-1 Inhibitors project).
| null |
LuciferaseInhibition
| null | 602,357
| null | 104
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate
| null |
LuciferaseInhibition
| null | 602,358
| null | 102
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate and 500microM CoASH
| null |
LuciferaseInhibition
| null | 602,364
| null | 89
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM ATP
| null |
LuciferaseInhibition
| null | 602,474
| null | 53
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a biochemical assay with a commercial detection reagent - BriteliteTM Plus (PerkinElmer)
| null |
LuciferaseInhibition
| null | 602,475
| null | 36
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a biochemical assay with an in-house formulation of detection reagent
| null |
LuciferaseInhibition
| null | 602,476
| null | 31
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a cell-based translational read-through assay
| null |
LuciferaseInhibition
| null | 602,477
| null | 87
| null | null | null |
FLuc inhibitory activity for the follow-up compounds in a cell-based assay to assess the activity of miR-21
| null |
LuciferaseInhibition
| null | 624,030
| null | 104
| null | null | null |
Biochemical firefly luciferase enzyme assay for NPC
| null |
LuciferaseInhibition
| null | 652,016
| null | 35
| null | null | null |
qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set
| null |
End of preview.